A few things that might help in that perspective are
Change the default location of the My Documents folder by following these steps. It helps rid of the windows drive clogging up with more files and space:
1.Click Start, and then point to My Documents.
2.Right-click My Documents, and then click Properties.
3.Click the Target tab.
4.In the Target box, do one of the following:
-->Type the path to the folder location that you want, and then click OK. For example, D:\My Stuff.
If the folder does not exist, the Create Message dialog box is displayed. Click Yes to create the folder, and then click OK.
-or-
--->Click Move, click the folder in which to store your documents, and then click OK twice.
If you need to create a new folder, click Make New Folder. Type a name for the folder, and then click OK twice.
5. In the Move Documents box, click Yes to move your documents to the new location, or click No to leave your documents in the original location.
Next you can try clearing your
%systemroot%\documents and settings\
\local settings\temp
-and-
%systemroot%\documents and settings\\local settings\temporary internet files
Some of the files in the temp wouldnt delete because they might be used by your OS so dont worry, the rest can be deleted and also any other folder under the or
Any error or message that it shows up dont worry, just clear it, coz your system will be free a bit more.
Another one is emptying of the rollback folders for all the updates done. You can delete them from your windows folder they start with $KB and uninst so you can take them out to save more space but remember once you do that you cannot uninstall the updates at a future time...Do it only if your system is working/ been working fine for a while...
These are a few tips after which you can try to defragment your drive
-->Start/All programs/accessories/system tools/disk defragmenter
Then before you start it remember to disable your screensaver and turn off your power saving settings. Once you complete this exercise it should be up and running great....Also if problems persist it is wise to use a anti-spy program and antivirus program.